What You Need to Know About Allina Health Care’s ‘First-in-Class’ Diabetes Treatment
The world’s largest diabetes treatment company is poised to deliver its first-in, first-out treatment of Type 1 diabetes on a large scale.
Allina is in talks to sell the insulin, which will be administered in a hospital setting.
“It will be the first of its kind for Type 1,” said Dr. Anthony J. Sussman, Allina’s chief medical officer.
All the major diabetes drug companies, including Pfizer, are trying to develop insulin that works in the hospital setting, but none of them are in the process of doing so yet.
In the United States, the only other diabetes drug company in the market is Novo Nordisk, which sells insulin in the lab for use in hospitals.
Allinan’s insulin is expected to cost $100,000, or about $5,000 per patient.
Its first drug, known as Orexin-1, is expected in the coming months, and is expected be used to treat patients with Type 1.
All in all, Allina has raised $8.5 billion in funding to date.
The company, which was founded in 2006 by the late George Grosz, is the world’s fifth-largest diabetes treatment firm by revenue, with $874 billion in revenues in 2018.
Allan is developing the insulin because its CEO, Paul J. Pate, has been involved in developing insulin for diabetes patients.
The insulin is designed to treat the body’s response to insulin and is based on an enzyme called AMPK that has been implicated in metabolic diseases such as obesity and diabetes.
In diabetes, AMPK, which is responsible for activating insulin receptors, is not involved in regulating blood sugar levels.
All of the other drugs in the pipeline are also insulin-based, and they are not designed to be used as primary therapies.
“I think the big challenge we face with insulin is the fact that it’s a synthetic enzyme that is very complex,” said J.D. Johnson, a professor of medicine and director of the National Institute on Aging Institute for Diabetes and Metabolic Disorders and Stroke Research.
“If you don’t know how to control AMPK in the body, the body cannot properly regulate blood sugar.”
For the patient to benefit from the insulin therapy, he said, the treatment should be done in the outpatient setting.
Patients will receive the treatment in the office, where they will have access to a clinic for insulin administration.
Dr. J.C. Martin, an associate professor of medical history at Northwestern University, said the technology has the potential to be an “extremely important tool” for patients, especially with Type 2 diabetes.
“The technology is not perfect,” Martin said.
“There’s a lot of research that needs to be done before we can say this is going to be a safe and effective treatment for the type 2 diabetic population.”
Dr. James C. Miller, an emergency medicine physician at Memorial Sloan Kettering Cancer Center, said that he is excited by Allina and Allinane.
“Allinane is going out of business because they have made a tremendous amount of progress in developing and using this new type of drug, which I think is a huge achievement for them,” Miller said.
The drug is in Phase 3 clinical trials and is being administered by doctors in hospitals in the United Kingdom and the United Arab Emirates.
In all, there are more than 20,000 Type 2 patients who have received treatment with the drug in the past six years.
In addition to Allinina, the drug company is in discussions with Eli Lilly and Johnson & Johnson to develop new drugs.
The new drugs will be available in Phase 2 clinical trials in the U.K. and the U